Model-based assessment of replicability for genome-wide association meta-analysis

Model-based assessment of replicability for genome-wide association meta-analysis

In genome-wide association meta-analysis, it is often difficult to find an independent dataset of sufficient size to replicate associations. Here, the authors have developed MAMBA to calculate the probability of replicability based on consistency between datasets within the meta-analysis.

Saved in:
Bibliographic Details
Main Authors: Daniel McGuire, Yu Jiang, Mengzhen Liu, J. Dylan Weissenkampen, Scott Eckert, Lina Yang, Fang Chen, GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN), Arthur Berg, Scott Vrieze, Bibo Jiang, Qunhua Li, Dajiang J. Liu
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/6c029971d51f400b8a1f25c6554953b1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/6c029971d51f400b8a1f25c6554953b1

Similar Items