Sublingual Immunization with Chimeric C1q/CD40 Ligand/HIV Virus-like Particles Induces Strong Mucosal Immune Responses against HIV

Development of a vaccine that can elicit robust HIV specific antibody responses in the mucosal compartments is desired for effective prevention of HIV via sexual transmission. However, the current mucosal vaccines have either poor immunogenicity when administered orally or invite safety concerns whe...

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Autores principales: Dongliang Liu, Sheng Zhang, Ethan Poteet, Christian Marin-Muller, Changyi Chen, Qizhi Yao
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
HIV
IgA
R
Acceso en línea:https://doaj.org/article/6c21dd1fa9064b90bb44df71145dae7d
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