Sublingual Immunization with Chimeric C1q/CD40 Ligand/HIV Virus-like Particles Induces Strong Mucosal Immune Responses against HIV

Development of a vaccine that can elicit robust HIV specific antibody responses in the mucosal compartments is desired for effective prevention of HIV via sexual transmission. However, the current mucosal vaccines have either poor immunogenicity when administered orally or invite safety concerns whe...

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Détails bibliographiques
Auteurs principaux: Dongliang Liu, Sheng Zhang, Ethan Poteet, Christian Marin-Muller, Changyi Chen, Qizhi Yao
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
HIV
IgA
R
Accès en ligne:https://doaj.org/article/6c21dd1fa9064b90bb44df71145dae7d
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