PIAS3 suppresses damage in an Alzheimer’s disease cell model by inducing the STAT3-associated STAT3/Nestin/Nrf2/HO-1 pathway

Abstract Background Alzheimer’s disease (AD), the most common form of dementia, is caused by the degeneration of the central nervous system (CNS). A previous study reported that signal transducer and activator of transcription 3 (STAT3) is activated during AD development; nonetheless, the related me...

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Auteurs principaux: Chen Li, Ruili Wang, Youyou Zhang, Chunting Hu, Qiaoya Ma
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/6c3b6354346f48fd8f7bda8a110db5d2
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