Diagnostic significance of intrathecally synthesized immunoglobulins against neurotropic viruses (MRZ-reaction) in diagnosis of multiple sclerosis

Diagnostic significance of intrathecally synthesized immunoglobulins against neurotropic viruses (MRZ-reaction) in diagnosis of multiple sclerosis

Multiple sclerosis is chronic demyelinating disease of the central nervous system with autoimmune inflammation and accretive neurodegeneration. One of the characteristics of autoimmune inflammation in multiple sclerosis is a polyspecific intrathecal humoral immune response against neurotropic viruse...

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Main Authors: A. N. Moshnikova, V. K. Maksimchuk, S. V. Lapin, V. D. Nazarov, E. A. Surkova, S. A. Novikov, G. S. Makshakov, I. Yu. Krutetskaya, V. S. Krasnov, Ya. B. Kushnir, N. A. Neofidov, N. A. Totolian, A. A. Skoromets, E. P. Evdoshenko, Areg A. Totolian
Format: article
Language:RU
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2020
Subjects:
multiple sclerosis
mrz-reaction
intrathecal synthesis of immunoglobulins
free light chains of immunoglobulins
oligoclonal igg
antibody indices
Infectious and parasitic diseases
RC109-216
Online Access:https://doaj.org/article/6c3d14a17f2a4c6ba344cb2e4b7914c4
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https://doaj.org/article/6c3d14a17f2a4c6ba344cb2e4b7914c4

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