Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus
ABSTRACT To transfer the viral genome into the host cell cytoplasm, internalized influenza A virus (IAV) particles depend on the fusion of the IAV envelope with host endosomal membranes. The antiviral host interferon (IFN) response includes the upregulation of interferon-induced transmembrane protei...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2018
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Acceso en línea: | https://doaj.org/article/6c3d712588c4446f9847a58b5227d3c0 |
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