Monoclonal antibodies to the V2 domain of MN-rgp120: fine mapping of epitopes and inhibition of α4β7 binding.

<h4>Background</h4>Recombinant gp120 (MN-rgp120) was a major component of the AIDSVAX B/E vaccine used in the RV144 trial. This was the first clinical trial to show that vaccination could prevent HIV infection in humans. A recent RV144 correlates of protection study found that protection...

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Auteurs principaux: Gerald R Nakamura, Dora P A J Fonseca, Sara M O'Rourke, Aaron L Vollrath, Phillip W Berman
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
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Accès en ligne:https://doaj.org/article/6c46fd26f6ae4b9d824b1a0d4b649222
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