Mechanochemical Synthesis of A Novel Eutectic of the Antimicrobial Nitazoxanide with Improved Dissolution Performance

Background: Nitazoxanide (NTZ) is a broad spectrum antimicrobial agent with poor aqueous solubility and low bioavailability. Thus, the generation of new solid forms of NTZ is relevant to improve its unfavorable properties. The present study deals with the application of mechanochemistry for the prep...

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Auteurs principaux: Octavio E. Fandiño, Flavia P Bruno, Gustavo A. Monti, Norma R. Sperandeo
Format: article
Langue:EN
Publié: Tabriz University of Medical Sciences 2021
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Accès en ligne:https://doaj.org/article/6c47f72ff9d34083b049dc5cd96f36b4
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