DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability

DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability

TATA-binding protein (TBP) and a transcription factor (TF) IIB-like factor are important constituents of all eukaryotic initiation complexes. Here, the authors use a DNA origami-based force clamp to investigate the assembly dynamics of human initiation complexes in the RNAP II and RNAP III systems a...

Full description

Saved in:
Bibliographic Details
Main Authors: Kevin Kramm, Tim Schröder, Jerome Gouge, Andrés Manuel Vera, Kapil Gupta, Florian B. Heiss, Tim Liedl, Christoph Engel, Imre Berger, Alessandro Vannini, Philip Tinnefeld, Dina Grohmann
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
Q
Online Access:https://doaj.org/article/6c52a4bb73744eafa2b7a2b2daca7321
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/6c52a4bb73744eafa2b7a2b2daca7321

Similar Items