Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells.
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens are reduced. Here, we demonstrate that malari...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2007
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| Subjects: | |
| Online Access: | https://doaj.org/article/6c6e1c6e87f9459890b2c00832c88a0b |
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