LRRK2 levels in immune cells are increased in Parkinson’s disease

Immune system regulation: A known suspect High levels of leucine-rich repeat kinase 2 (LRRK2) in immune cells disrupt immune system function in patients with Parkinson’s disease (PD). Mutations in LRRK2 are the most common genetic cause of PD. Although LRRK2 is found in many immune cells, research e...

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Auteurs principaux: D. A. Cook, G. T. Kannarkat, A. F. Cintron, Laura M. Butkovich, Kyle B. Fraser, J. Chang, N. Grigoryan, S. A. Factor, Andrew B. West, J. M. Boss, M. G. Tansey
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/6c926ddf8a1d4b89b93c4407e58bb695
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