Testosterone increases susceptibility to amebic liver abscess in mice and mediates inhibition of IFNγ secretion in natural killer T cells.

Amebic liver abscess (ALA), a parasitic disease due to infection with the protozoan Entamoeba histolytica, occurs age and gender dependent with strong preferences for adult males. Using a mouse model for ALA with a similar male bias for the disease, we have investigated the role of female and male s...

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Autores principales: Hannelore Lotter, Elena Helk, Hannah Bernin, Thomas Jacobs, Cornelia Prehn, Jerzy Adamski, Nestor González-Roldán, Otto Holst, Egbert Tannich
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/6cb17ea7d3104511a66855a470eb789f
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