Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1.
<h4>Background</h4>Microtubule-targeting drugs induce mitotic delay at pro-metaphase by preventing the spindle assembly checkpoint to be satisfied. However, especially after prolonged treatments, cells can escape this arrest in a process called mitotic slippage. The mechanisms underlying...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
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| Accès en ligne: | https://doaj.org/article/6cbeb95a029543c4ba9004c19b55beb2 |
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