Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1.

<h4>Background</h4>Microtubule-targeting drugs induce mitotic delay at pro-metaphase by preventing the spindle assembly checkpoint to be satisfied. However, especially after prolonged treatments, cells can escape this arrest in a process called mitotic slippage. The mechanisms underlying...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ana Lúcia Mena, Eric W-F Lam, Sukalyan Chatterjee
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
R
Q
Acceso en línea:https://doaj.org/article/6cbeb95a029543c4ba9004c19b55beb2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares