Chiral Resolution, Absolute Configuration Assignment, and Genotoxicity Evaluation of Racemic 3,4-Dihydroquinazoline as a Novel Anticancer Agent
If a new drug candidate will be a mixture of enantiomers, both enantiomers should be separately studied for at least latent genotoxicity as early as possible since the thalidomide tragedy. Our group has recently reported that KCP-10043F (OZ-001) as a racemate (±)-3,4-dihydroquinazoline derivative st...
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Formato: | article |
Lenguaje: | EN |
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Hindawi Limited
2021
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Acceso en línea: | https://doaj.org/article/6cdb29ca810b425c8948cc86c2aa4421 |
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