Pharmacometabolomics identifies candidate predictor metabolites of an L‐carnitine treatment mortality benefit in septic shock
Abstract Sepsis‐induced metabolic dysfunction contributes to organ failure and death. L‐carnitine has shown promise for septic shock, but a recent phase II study of patients with vasopressor‐dependent septic shock demonstrated a non‐significant reduction in mortality. We undertook a pharmacometabolo...
Saved in:
Main Authors: | Michael A. Puskarich, Theodore S. Jennaro, Christopher E. Gillies, Charles R. Evans, Alla Karnovsky, Cora E. McHugh, Thomas L. Flott, Alan E. Jones, Kathleen A. Stringer, for the RACE Investigators |
---|---|
Format: | article |
Language: | EN |
Published: |
Wiley
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/6ce1ffd631774c4e9df4a19cf077f90d |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients
by: Bora Kim, et al.
Published: (2017) -
Effects of therapeutic plasma exchange on the endothelial glycocalyx in septic shock
by: Klaus Stahl, et al.
Published: (2021) -
Septic shock: perspective methods of diagnostics and therapy based on immunopathogenesis
by: L. I. Gomanova
Published: (2020) -
Meningocoxemic Septic Shock; A Case Report and Review of the Literature
by: Murat Özkale, et al.
Published: (2021) -
Telomere shortening during human septic shock: influence of sepsis mediators, role in organ failures, and septic myocardial dysfunction
by: Keyvan Razazi, et al.
Published: (2021)