A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme

Adventitious oxidation of erythrose-4-phosphate generates 4-phosphoerythronate, which is detoxified by metabolite-proofreading phosphatases in eukaryotes. Here, Sachla & Helmann show that a similar function is carried out in Bacillus subtilis by a checkpoint protein involved in ribosome assembly...

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Autores principales: Ankita J. Sachla, John D. Helmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6cfb84cfe69b4fd7bc8edc1f4efd293f
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