A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme

Adventitious oxidation of erythrose-4-phosphate generates 4-phosphoerythronate, which is detoxified by metabolite-proofreading phosphatases in eukaryotes. Here, Sachla & Helmann show that a similar function is carried out in Bacillus subtilis by a checkpoint protein involved in ribosome assembly...

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Autores principales:	Ankita J. Sachla, John D. Helmann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6cfb84cfe69b4fd7bc8edc1f4efd293f
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spelling	oai:doaj.org-article:6cfb84cfe69b4fd7bc8edc1f4efd293f2021-12-02T15:35:32ZA bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme10.1038/s41467-019-09508-z2041-1723https://doaj.org/article/6cfb84cfe69b4fd7bc8edc1f4efd293f2019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09508-zhttps://doaj.org/toc/2041-1723Adventitious oxidation of erythrose-4-phosphate generates 4-phosphoerythronate, which is detoxified by metabolite-proofreading phosphatases in eukaryotes. Here, Sachla & Helmann show that a similar function is carried out in Bacillus subtilis by a checkpoint protein involved in ribosome assembly.Ankita J. SachlaJohn D. HelmannNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ankita J. Sachla John D. Helmann A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
description	Adventitious oxidation of erythrose-4-phosphate generates 4-phosphoerythronate, which is detoxified by metabolite-proofreading phosphatases in eukaryotes. Here, Sachla & Helmann show that a similar function is carried out in Bacillus subtilis by a checkpoint protein involved in ribosome assembly.
format	article
author	Ankita J. Sachla John D. Helmann
author_facet	Ankita J. Sachla John D. Helmann
author_sort	Ankita J. Sachla
title	A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
title_short	A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
title_full	A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
title_fullStr	A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
title_full_unstemmed	A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
title_sort	bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6cfb84cfe69b4fd7bc8edc1f4efd293f
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A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme

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