A bacterial checkpoint protein for ribosome assembly moonlights as an essential metabolite-proofreading enzyme
Adventitious oxidation of erythrose-4-phosphate generates 4-phosphoerythronate, which is detoxified by metabolite-proofreading phosphatases in eukaryotes. Here, Sachla & Helmann show that a similar function is carried out in Bacillus subtilis by a checkpoint protein involved in ribosome assembly...
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Autores principales: | Ankita J. Sachla, John D. Helmann |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/6cfb84cfe69b4fd7bc8edc1f4efd293f |
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