Ionizable lipid-assisted efficient hepatic delivery of gene editing elements for oncotherapy
CRISPR/Cas9-based gene editing has emerged as a powerful biotechnological tool, that relies on Cas9 protein and single guided RNA (sgRNA) to edit target DNA. However, the lack of safe and efficient delivery carrier is one of the crucial factors restricting its clinical transformation. Here, we repor...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
KeAi Communications Co., Ltd.
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/6d004e3692a447fa8672c0d2cf7c8d45 |
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