Ionizable lipid-assisted efficient hepatic delivery of gene editing elements for oncotherapy
CRISPR/Cas9-based gene editing has emerged as a powerful biotechnological tool, that relies on Cas9 protein and single guided RNA (sgRNA) to edit target DNA. However, the lack of safe and efficient delivery carrier is one of the crucial factors restricting its clinical transformation. Here, we repor...
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Autores principales: | Chunhui Li, Tongren Yang, Yuhua Weng, Mengjie Zhang, Deyao Zhao, Shuai Guo, Bo Hu, Wanxuan Shao, Xiaoxia Wang, Abid Hussain, Xing-Jie Liang, Yuanyu Huang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
KeAi Communications Co., Ltd.
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/6d004e3692a447fa8672c0d2cf7c8d45 |
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