Cortical glutamate and gamma-aminobutyric acid over the course of a provoked migraine attack, a 7 Tesla magnetic resonance spectroscopy study

Enhanced activity of the glutamatergic system has been linked to migraine pathophysiology. The present study aimed to assess the involvement of the glutamatergic system in the onset of attacks. We provoked attacks by infusion of glyceryl trinitrate (GTN; 0.5 µg/kg/min over 20 min) in 24 female episo...

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Autores principales: Gerrit L.J. Onderwater, Jannie P. Wijnen, Chloé Najac, Robin M. van Dongen, Itamar Ronen, Andrew Webb, Ronald Zielman, Erik W. van Zwet, Michel D. Ferrari, Hermien E. Kan, Mark C. Kruit, Gisela M. Terwindt
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/6d0bb6880d1d42249173dbcdc062378b
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