Cortical glutamate and gamma-aminobutyric acid over the course of a provoked migraine attack, a 7 Tesla magnetic resonance spectroscopy study

Cortical glutamate and gamma-aminobutyric acid over the course of a provoked migraine attack, a 7 Tesla magnetic resonance spectroscopy study

Enhanced activity of the glutamatergic system has been linked to migraine pathophysiology. The present study aimed to assess the involvement of the glutamatergic system in the onset of attacks. We provoked attacks by infusion of glyceryl trinitrate (GTN; 0.5 µg/kg/min over 20 min) in 24 female episo...

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Bibliographic Details
Main Authors: Gerrit L.J. Onderwater, Jannie P. Wijnen, Chloé Najac, Robin M. van Dongen, Itamar Ronen, Andrew Webb, Ronald Zielman, Erik W. van Zwet, Michel D. Ferrari, Hermien E. Kan, Mark C. Kruit, Gisela M. Terwindt
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Migraine
Glutamate
GABA
Magnetic resonance spectroscopy
Glyceryl trinitrate
Computer applications to medicine. Medical informatics
R858-859.7
Neurology. Diseases of the nervous system
RC346-429
Online Access:https://doaj.org/article/6d0bb6880d1d42249173dbcdc062378b
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