Mammalian expression of virus-like particles as a proof of principle for next generation polio vaccines

Abstract Global vaccination programs using live-attenuated oral and inactivated polio vaccine (OPV and IPV) have almost eradicated poliovirus (PV) but these vaccines or their production pose significant risk in a polio-free world. Recombinant PV virus-like particles (VLPs), lacking the viral genome,...

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Autores principales: Mohammad W. Bahar, Claudine Porta, Helen Fox, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6d14a9581b7346d2a0e7c0c7fcf06ddd
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