Cell Cycle Regulation by Alternative Polyadenylation of CCND1

Abstract Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown. CCND1 is a proto-oncogene that regulates progression through the G1-S phase of the cell cycle; moreover, it has been observed to be switchi...

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Autores principales: Qiong Wang, Guopei He, Mengmeng Hou, Liutao Chen, Shangwu Chen, Anlong Xu, Yonggui Fu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6d2ecd47812c4c7a822f6dc174b416a0
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