Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei

The structure and dynamics of large proteins and complexes can be studied by methyl-NMR but resonance assignment is still challenging. Here, the authors present a NMR method that leverages optimal control pulse design to unambiguously distinguish between Leu and Val using a simple 2D HMQC experiment...

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Autores principales: Soumya P. Behera, Abhinav Dubey, Wan-Na Chen, Viviane S. De Paula, Meng Zhang, Nikolaos G. Sgourakis, Wolfgang Bermel, Gerhard Wagner, Paul W. Coote, Haribabu Arthanari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6d3ce66bd2fb4ffa8c649ac9c398510f
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