Tumorigenic potential of olfactory bulb-derived human adult neural stem cells associates with activation of TERT and NOTCH1.

<h4>Background</h4>Multipotent neural stem cells (NSCs) have been isolated from neurogenic regions of the adult brain. Reportedly, these cells can be expanded in vitro under prolonged mitogen stimulation without propensity to transform. However, the constitutive activation of the cellula...

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Auteurs principaux: Patrizia Casalbore, Manuela Budoni, Lucia Ricci-Vitiani, Carlo Cenciarelli, Giovanna Petrucci, Luisa Milazzo, Nicola Montano, Elisabetta Tabolacci, Giulio Maira, Luigi M Larocca, Roberto Pallini
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/6d40434030974edb81d0b71291bb8688
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