Clostridial glucosylating toxins enter cells via clathrin-mediated endocytosis.

Clostridium difficile toxin A (TcdA) and toxin B (TcdB), C. sordellii lethal toxin (TcsL) and C. novyi alpha-toxin (TcnA) are important pathogenicity factors, which represent the family of the clostridial glucosylating toxins (CGTs). Toxin A and B are associated with antibiotic-associated diarrhea a...

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Bibliographic Details
Main Authors: Panagiotis Papatheodorou, Constantinos Zamboglou, Selda Genisyuerek, Gregor Guttenberg, Klaus Aktories
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
R
Q
Online Access:https://doaj.org/article/6d55c26786ba4fe9ae94fe055c128f32
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