Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

Abstract Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonly used to treat type 2 diabetes, has been associat...

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Autores principales: Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6d775d6752384370af9c1a1651d89e30
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