Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

Abstract Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a metabolic drug commonly used to treat type 2 diabetes, has been associat...

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Autores principales: Abdelnour H. Alhourani, Tia R. Tidwell, Ansooya A. Bokil, Gro V. Røsland, Karl Johan Tronstad, Kjetil Søreide, Hanne R. Hagland
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6d775d6752384370af9c1a1651d89e30
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