Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors
York et al employ lattice light-sheet microscopy to study the initial events following activation of the epidermal growth factor receptor (EGFR) in whole live cells. They find that APPL1 relocates from pre-existing endosomes, triggered by calcium, to EGFR puncta which results in a cohort, dynein med...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6d8be203c19f405a981ea451a9628361 |
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