Improvement in aqueous solubility of achiral symmetric cyclofenil by modification to a chiral asymmetric analog
Abstract Decreasing the partition coefficient (LogP) by the introduction of a hydrophilic group is the conventional approach for improving the aqueous solubility of drug candidates, but is not always effective. Since melting point is related to aqueous solubility, we and other groups have developed...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/6da4c61e46e044feab315317688174ce |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|