Pain in adults with congenital heart disease - An international perspective
Background: Patients with adult congenital heart disease (ACHD) have many risk factors for chronic pain such as prior cardiac interventions and adult comorbidities. However, the prevalence of chronic pain has not been well described in this population. We sought to determine the prevalence of pain i...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6dbbeef907364f189dffb44ac49f9d5a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6dbbeef907364f189dffb44ac49f9d5a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6dbbeef907364f189dffb44ac49f9d5a2021-11-06T04:37:26ZPain in adults with congenital heart disease - An international perspective2666-668510.1016/j.ijcchd.2021.100200https://doaj.org/article/6dbbeef907364f189dffb44ac49f9d5a2021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666668521001245https://doaj.org/toc/2666-6685Background: Patients with adult congenital heart disease (ACHD) have many risk factors for chronic pain such as prior cardiac interventions and adult comorbidities. However, the prevalence of chronic pain has not been well described in this population. We sought to determine the prevalence of pain in a large international cohort of patients with ACHD. Methods: Data from the APPROACH-IS dataset was utilized for this study which includes 4028 patients with ACHD from 15 different countries. The prevalence of pain was assessed under the health status patient reported outcome domain utilizing the EuroQol-5D 3 level version tool. Multivariable logistic regression was used to assess differences across countries in pain, taking into account country-level random effects for clustering across observations within each country. Results: A total of 3832 patients with ACHD met the study criteria, median age 32 years [IQR 25, 42], 52.6% females. The prevalence of at least moderate pain was reported by 28.9% (95% CO 27.5 = 30.3%) of participants. Pain was associated with country of origin, age, gender, background, education and marital status as well as several clinical variables including disease complexity, cardiac device presence, history of heart failure, psychiatric conditions and presence of other medical conditions. Those with pain had lower levels of perceived health and a lower quality of life score. Conclusion: Pain in patients with ACHD is common, impacting nearly one-third of patients. Given the far reaching implications of pain in patients with ACHD, further study of pain characteristics and treatment management appear warranted.Allison LeiboldErin EichlerSukyung ChungPhilip MoonsAdrienne H. KovacsKoen LuyckxSilke ApersCorina ThometWerner BudtsJunko EnomotoMaayke A. SlumanJou-Kou WangJamie L. JacksonPaul KhairyStephen C. CookShanthi ChidambarathanuLuis AldayErwin OechslinKatrine EriksenMikael DellborgMalin BerghammerBengt JohanssonAndrew S. MackieSamuel MenahemMaryanne CaruanaGruschen VeldtmanAlexandra SoufiKamila WhiteEdward CallusShelby KuttySusan M. FernandesElsevierarticleAdult congenital heart diseaseCongenital heart diseaseChronic painPatient reported outcomesDiseases of the circulatory (Cardiovascular) systemRC666-701ENInternational Journal of Cardiology Congenital Heart Disease, Vol 5, Iss , Pp 100200- (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Adult congenital heart disease Congenital heart disease Chronic pain Patient reported outcomes Diseases of the circulatory (Cardiovascular) system RC666-701 |
| spellingShingle |
Adult congenital heart disease Congenital heart disease Chronic pain Patient reported outcomes Diseases of the circulatory (Cardiovascular) system RC666-701 Allison Leibold Erin Eichler Sukyung Chung Philip Moons Adrienne H. Kovacs Koen Luyckx Silke Apers Corina Thomet Werner Budts Junko Enomoto Maayke A. Sluman Jou-Kou Wang Jamie L. Jackson Paul Khairy Stephen C. Cook Shanthi Chidambarathanu Luis Alday Erwin Oechslin Katrine Eriksen Mikael Dellborg Malin Berghammer Bengt Johansson Andrew S. Mackie Samuel Menahem Maryanne Caruana Gruschen Veldtman Alexandra Soufi Kamila White Edward Callus Shelby Kutty Susan M. Fernandes Pain in adults with congenital heart disease - An international perspective |
| description |
Background: Patients with adult congenital heart disease (ACHD) have many risk factors for chronic pain such as prior cardiac interventions and adult comorbidities. However, the prevalence of chronic pain has not been well described in this population. We sought to determine the prevalence of pain in a large international cohort of patients with ACHD. Methods: Data from the APPROACH-IS dataset was utilized for this study which includes 4028 patients with ACHD from 15 different countries. The prevalence of pain was assessed under the health status patient reported outcome domain utilizing the EuroQol-5D 3 level version tool. Multivariable logistic regression was used to assess differences across countries in pain, taking into account country-level random effects for clustering across observations within each country. Results: A total of 3832 patients with ACHD met the study criteria, median age 32 years [IQR 25, 42], 52.6% females. The prevalence of at least moderate pain was reported by 28.9% (95% CO 27.5 = 30.3%) of participants. Pain was associated with country of origin, age, gender, background, education and marital status as well as several clinical variables including disease complexity, cardiac device presence, history of heart failure, psychiatric conditions and presence of other medical conditions. Those with pain had lower levels of perceived health and a lower quality of life score. Conclusion: Pain in patients with ACHD is common, impacting nearly one-third of patients. Given the far reaching implications of pain in patients with ACHD, further study of pain characteristics and treatment management appear warranted. |
| format |
article |
| author |
Allison Leibold Erin Eichler Sukyung Chung Philip Moons Adrienne H. Kovacs Koen Luyckx Silke Apers Corina Thomet Werner Budts Junko Enomoto Maayke A. Sluman Jou-Kou Wang Jamie L. Jackson Paul Khairy Stephen C. Cook Shanthi Chidambarathanu Luis Alday Erwin Oechslin Katrine Eriksen Mikael Dellborg Malin Berghammer Bengt Johansson Andrew S. Mackie Samuel Menahem Maryanne Caruana Gruschen Veldtman Alexandra Soufi Kamila White Edward Callus Shelby Kutty Susan M. Fernandes |
| author_facet |
Allison Leibold Erin Eichler Sukyung Chung Philip Moons Adrienne H. Kovacs Koen Luyckx Silke Apers Corina Thomet Werner Budts Junko Enomoto Maayke A. Sluman Jou-Kou Wang Jamie L. Jackson Paul Khairy Stephen C. Cook Shanthi Chidambarathanu Luis Alday Erwin Oechslin Katrine Eriksen Mikael Dellborg Malin Berghammer Bengt Johansson Andrew S. Mackie Samuel Menahem Maryanne Caruana Gruschen Veldtman Alexandra Soufi Kamila White Edward Callus Shelby Kutty Susan M. Fernandes |
| author_sort |
Allison Leibold |
| title |
Pain in adults with congenital heart disease - An international perspective |
| title_short |
Pain in adults with congenital heart disease - An international perspective |
| title_full |
Pain in adults with congenital heart disease - An international perspective |
| title_fullStr |
Pain in adults with congenital heart disease - An international perspective |
| title_full_unstemmed |
Pain in adults with congenital heart disease - An international perspective |
| title_sort |
pain in adults with congenital heart disease - an international perspective |
| publisher |
Elsevier |
| publishDate |
2021 |
| url |
https://doaj.org/article/6dbbeef907364f189dffb44ac49f9d5a |
| work_keys_str_mv |
AT allisonleibold paininadultswithcongenitalheartdiseaseaninternationalperspective AT erineichler paininadultswithcongenitalheartdiseaseaninternationalperspective AT sukyungchung paininadultswithcongenitalheartdiseaseaninternationalperspective AT philipmoons paininadultswithcongenitalheartdiseaseaninternationalperspective AT adriennehkovacs paininadultswithcongenitalheartdiseaseaninternationalperspective AT koenluyckx paininadultswithcongenitalheartdiseaseaninternationalperspective AT silkeapers paininadultswithcongenitalheartdiseaseaninternationalperspective AT corinathomet paininadultswithcongenitalheartdiseaseaninternationalperspective AT wernerbudts paininadultswithcongenitalheartdiseaseaninternationalperspective AT junkoenomoto paininadultswithcongenitalheartdiseaseaninternationalperspective AT maaykeasluman paininadultswithcongenitalheartdiseaseaninternationalperspective AT joukouwang paininadultswithcongenitalheartdiseaseaninternationalperspective AT jamieljackson paininadultswithcongenitalheartdiseaseaninternationalperspective AT paulkhairy paininadultswithcongenitalheartdiseaseaninternationalperspective AT stephenccook paininadultswithcongenitalheartdiseaseaninternationalperspective AT shanthichidambarathanu paininadultswithcongenitalheartdiseaseaninternationalperspective AT luisalday paininadultswithcongenitalheartdiseaseaninternationalperspective AT erwinoechslin paininadultswithcongenitalheartdiseaseaninternationalperspective AT katrineeriksen paininadultswithcongenitalheartdiseaseaninternationalperspective AT mikaeldellborg paininadultswithcongenitalheartdiseaseaninternationalperspective AT malinberghammer paininadultswithcongenitalheartdiseaseaninternationalperspective AT bengtjohansson paininadultswithcongenitalheartdiseaseaninternationalperspective AT andrewsmackie paininadultswithcongenitalheartdiseaseaninternationalperspective AT samuelmenahem paininadultswithcongenitalheartdiseaseaninternationalperspective AT maryannecaruana paininadultswithcongenitalheartdiseaseaninternationalperspective AT gruschenveldtman paininadultswithcongenitalheartdiseaseaninternationalperspective AT alexandrasoufi paininadultswithcongenitalheartdiseaseaninternationalperspective AT kamilawhite paininadultswithcongenitalheartdiseaseaninternationalperspective AT edwardcallus paininadultswithcongenitalheartdiseaseaninternationalperspective AT shelbykutty paininadultswithcongenitalheartdiseaseaninternationalperspective AT susanmfernandes paininadultswithcongenitalheartdiseaseaninternationalperspective |
| _version_ |
1718443857883955200 |