Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action
Summary: Ketamine is a noncompetitive glutamatergic N-methyl-d-aspartate receptor (NMDAR) antagonist that exerts rapid antidepressant effects. Preclinical studies identify eukaryotic elongation factor 2 kinase (eEF2K) signaling as essential for the rapid antidepressant action of ketamine. Here, we c...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/6dd69221221e448c8ccdfbb132cd2ff5 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|