Dll4-notch signalling blockade synergizes combined ultrasound-stimulated microbubble and radiation therapy in human colon cancer xenografts.

Tumour vasculature acts as an essential lifeline for tumour progression and facilitates metastatic spread. Novel vascular targeting strategies aiming to sustain vascular shutdown could potentially induce substantial damage, resulting in a significant tumour growth delay. We investigated the combinat...

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Autores principales: Ahmed El Kaffas, Joris Nofiele, Anoja Giles, Song Cho, Stanley K Liu, Gregory J Czarnota
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/6dea36b544c2426b932a4f31009cd6c5
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