Topological Analysis of γH2AX and MRE11 Clusters Detected by Localization Microscopy during X-ray-Induced DNA Double-Strand Break Repair

DNA double-strand breaks (DSBs), known as the most severe damage in chromatin, were induced in breast cancer cells and normal skin fibroblasts by 2 Gy ionizing photon radiation. In response to DSB induction, phosphorylation of the histone variant H2AX to γH2AX was observed in the form of foci visual...

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Bibliographic Details
Main Authors: Hannes Hahn, Charlotte Neitzel, Olga Kopečná, Dieter W. Heermann, Martin Falk, Michael Hausmann
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/6e2f640b0aaf4e23ae74e77077dccded
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