Dose-dependent effects of Hedyotis diffusa extract on the pharmacokinetics of tamoxifen, 4-hydroxytamoxifen, and N-desmethyltamoxifen

Tamoxifen, a widely prescribed medication in premenopausal women diagnosed with hormone-dependent breast cancer, is potentially co-prescribed with Hedyotis diffusa (H. diffusa), particularly in Taiwan. However, no related report has investigated the drug-herb interaction of H. diffusa on the pharmac...

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Autores principales: Yung-Yi Cheng, Elise T. Tuzo, Jeffrey W. Dalley, Tung-Hu Tsai
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/6e520603c9484046a50077cffff07e98
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