Transcriptional Heterogeneity of <italic toggle="yes">Cryptococcus gattii</italic> VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways

Transcriptional Heterogeneity of <italic toggle="yes">Cryptococcus gattii</italic> VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways

ABSTRACT Cryptococcus gattii is a pathogenic yeast of humans and other animals which causes disease predominantly in immunocompetent hosts. Infection begins when aerosolized yeast or spores enter the body, triggering an immune response, including engulfment by macrophages. To understand the early tr...

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Autores principales: Rhys A. Farrer, Christopher B. Ford, Johanna Rhodes, Toni Delorey, Robin C. May, Matthew C. Fisher, Elaine Cloutman-Green, Francois Balloux, Christina A. Cuomo
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2018
Materias:
Cryptococcus
capsule
ergosterol
host response
host-pathogen interactions
laccase
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/6e68a9721caa4eaca8e2abf7fd098260
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https://doaj.org/article/6e68a9721caa4eaca8e2abf7fd098260

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