P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
Abstract In Alzheimer’s disease and related tauopathies, trans-synaptic transfer and accumulation of pathological tau from donor to recipient neurons is thought to contribute to disease progression, but the underlying mechanisms are poorly understood. Using complementary in vivo and in vitro models,...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
BMC
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/6ec10d2a588a40fb82206e796520623e |
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