P62 accumulates through neuroanatomical circuits in response to tauopathy propagation
Abstract In Alzheimer’s disease and related tauopathies, trans-synaptic transfer and accumulation of pathological tau from donor to recipient neurons is thought to contribute to disease progression, but the underlying mechanisms are poorly understood. Using complementary in vivo and in vitro models,...
Guardado en:
Autores principales: | François-Xavier Blaudin de Thé, Benjamin Lassus, Ari W. Schaler, Stephanie L. Fowler, Chris N. Goulbourne, Ross Jeggo, Clotilde Mannoury la Cour, Mark J. Millan, Karen E. Duff |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
BMC
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6ec10d2a588a40fb82206e796520623e |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
DNA Methylation in Genetic and Sporadic Forms of Neurodegeneration: Lessons from Alzheimer’s, Related Tauopathies and Genetic Tauopathies
por: Geraldine Zimmer-Bensch, et al.
Publicado: (2021) -
Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies
por: Emily Miyoshi, et al.
Publicado: (2021) -
GM3 Ganglioside Linked to Neurofibrillary Pathology in a Transgenic Rat Model for Tauopathy
por: Dominika Olešová, et al.
Publicado: (2021) -
18F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies
por: Michinori Ezura, et al.
Publicado: (2021) -
Prognostic Value of LC3B and p62 Expression in Small Intestinal Adenocarcinoma
por: Jeong-Won Kim, et al.
Publicado: (2021)