An adaptive method of defining negative mutation status for multi-sample comparison using next-generation sequencing

Abstract Background Multi-sample comparison is commonly used in cancer genomics studies. By using next-generation sequencing (NGS), a mutation's status in a specific sample can be measured by the number of reads supporting mutant or wildtype alleles. When no mutant reads are detected, it could...

Full description

Saved in:

Bibliographic Details
Main Authors:	Nicholas Hutson, Fenglin Zhan, James Graham, Mitsuko Murakami, Han Zhang, Sujana Ganaparti, Qiang Hu, Li Yan, Changxing Ma, Song Liu, Jun Xie, Lei Wei
Format:	article
Language:	EN
Published:	BMC 2021
Subjects:	Negative status Tumor heterogeneity Liquid biopsy Next-generation sequencing Genetic testing Personalized medicine Internal medicine RC31-1245 Genetics QH426-470
Online Access:	https://doaj.org/article/6ec5c0fa598645aab0521a3ef24101c0
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

An adaptive method of defining negative mutation status for multi-sample comparison using next-generation sequencing

Similar Items