Modelling of substrate access and substrate binding to cephalosporin acylases

Abstract Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternat...

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Autores principales: Valerio Ferrario, Mona Fischer, Yushan Zhu, Jürgen Pleiss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6ec7e748467a4151899601d6033f6264
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