Modelling of substrate access and substrate binding to cephalosporin acylases
Abstract Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternat...
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Autores principales: | Valerio Ferrario, Mona Fischer, Yushan Zhu, Jürgen Pleiss |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/6ec7e748467a4151899601d6033f6264 |
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