Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts
Little is known about the pathways that maintain mitochondrial structure and function under neuronal stress conditions. Here, authors demonstrate that the Mul1-Mfn2 pathway plays a checkpoint role in maintaining mitochondrial integrity and energy maintenance by ensuring ER-mitochondrial tethering an...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/6f1424b4200a43308728c4d36f509016 |
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