Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells

Tobacco smoking is the top risk factor for lung cancer development. Nicotine in cigarettes can induce addiction, and its derivatives become potent carcinogens after metabolic activation and activate oncogenic signaling in lung epithelial cells through their expressed nicotinic acetylcholine receptor...

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Bibliographic Details
Main Authors: Hoi-Hin Kwok, Boning Gao, Koon-Ho Chan, Mary Sau-Man Ip, John Dorrance Minna, David Chi-Leung Lam
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/6f3d049dbfe547e492a1d6aef1a24d41
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