Replication independent formation of extrachromosomal circular DNA in mammalian cell-free system.
Extrachromosomal circular DNA (eccDNA) is a pool of circular double stranded DNA molecules found in all eukaryotic cells and composed of repeated chromosomal sequences. It was proposed to be involved in genomic instability, aging and alternative telomere lengthening. Our study presents novel mammali...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2009
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| Accès en ligne: | https://doaj.org/article/6f4f0ebc7ee44eaf9423cfea177f545c |
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