Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy

Abstract Advancements in systems biology have resulted in the development of network pharmacology, leading to a paradigm shift from “one-target, one-drug” to “target-network, multi-component therapeutics”. We employ a chimeric approach involving in-vivo assays, gene expression analysis, cheminformat...

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Bibliographic Details
Main Authors: Aparna Rai, Vikas Kumar, Gaurav Jerath, C. C. Kartha, Vibin Ramakrishnan
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/6f53b632952146e7b40af56c91c87711
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