Targeting fidelity of adenine and cytosine base editors in mouse embryos

Understanding the risks of bystander and off-target editing is essential for genome engineering applications. Here, the authors analyze the fidelity of adenine and cytosine base editors in vivo.

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Bibliographic Details
Main Authors: Hye Kyung Lee, Michaela Willi, Shannon M. Miller, Sojung Kim, Chengyu Liu, David R. Liu, Lothar Hennighausen
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/6f5a2eab54b647bf9d594d5cbd192da5
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