Oral tolerance to cancer can be abrogated by T regulatory cell inhibition.

Oral administration of tumour cells induces an immune hypo-responsiveness known as oral tolerance. We have previously shown that oral tolerance to a cancer is tumour antigen specific, non-cross-reactive and confers a tumour growth advantage. We investigated the utilisation of regulatory T cell (Treg...

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Bibliographic Details
Main Authors: Maria C Whelan, Garrett Casey, John O Larkin, Barbara-ann Guinn, Gerald C O'Sullivan, Mark Tangney
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/6fb9eb08e7824095812a83065933474d
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