Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

Poly(ADP-ribose) glycohydrolase (PARG) is involved in different cellular processes including DNA repair. Here the authors reveal a role for PARG in regulating meiotic DNA double strand break induction and repair in Caenorhabditis elegans.

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Autores principales: Eva Janisiw, Marilina Raices, Fabiola Balmir, Luis F. Paulin, Antoine Baudrimont, Arndt von Haeseler, Judith L. Yanowitz, Verena Jantsch, Nicola Silva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6fbdd58c4ad94b98ba5e66e4807523fd
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